Alan Wells Selected Research

Inflammasomes

1/2021	Dysregulation of the mevalonate pathway during SARS-CoV-2 infection: An in silico study.
10/2017	MyD88-dependent inflammasome activation and autophagy inhibition contributes to Ehrlichia-induced liver injury and toxic shock.

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Alan Wells Research Topics

Disease

52	Neoplasms (Cancer) 11/2023 - 01/2002
24	Wounds and Injuries (Trauma) 01/2022 - 01/2002
21	Neoplasm Metastasis (Metastasis) 01/2023 - 01/2003
19	Breast Neoplasms (Breast Cancer) 10/2021 - 07/2003
17	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 04/2002
16	Carcinoma (Carcinomatosis) 12/2019 - 01/2002
14	COVID-19 11/2023 - 06/2020
10	Cicatrix (Scar) 01/2022 - 12/2006
8	Melanoma (Melanoma, Malignant) 01/2023 - 07/2010
6	Inflammation (Inflammations) 01/2024 - 01/2012
6	Neoplasm Micrometastasis 01/2022 - 01/2008
4	Squamous Cell Carcinoma of Head and Neck 07/2008 - 09/2003
3	HIV Infections (HIV Infection) 01/2022 - 01/2022
3	Starvation 01/2018 - 01/2008
2	Triple Negative Breast Neoplasms 10/2021 - 06/2012
2	Hematologic Neoplasms (Hematological Malignancy) 07/2021 - 04/2021
2	Blister (Bulla) 01/2021 - 10/2020
2	Glaucoma 01/2021 - 10/2020
2	Fibrosis (Cirrhosis) 01/2021 - 05/2011
2	Neurodevelopmental Disorders 01/2020 - 10/2018
2	Schizophrenia (Dementia Praecox) 01/2020 - 10/2018
2	Autism Spectrum Disorder 01/2020 - 10/2018
2	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 10/2019 - 01/2010
2	Infections 11/2017 - 10/2017
2	Glioblastoma (Glioblastoma Multiforme) 10/2008 - 01/2002
2	Keloid 07/2006 - 03/2004
1	Human Influenza (Influenza) 03/2024

Drug/Important Bio-Agent (IBA)

20	Proteins (Proteins, Gene)FDA Link 01/2023 - 06/2003
18	Cadherins (E-Cadherin)IBA 01/2022 - 01/2008
14	ErbB Receptors (EGF Receptor)IBA 01/2021 - 01/2002
13	CollagenIBA 01/2022 - 09/2003
12	CytokinesIBA 01/2022 - 03/2005
10	Epidermal Growth Factor (EGF)IBA 01/2021 - 08/2003
9	LigandsIBA 01/2021 - 09/2003
8	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 11/2023 - 12/2014
7	matrigelIBA 01/2013 - 06/2002
7	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 06/2012 - 01/2002
6	ChemokinesIBA 01/2022 - 01/2002
6	CalpainIBA 03/2011 - 01/2002
5	Atorvastatin (Lipitor)FDA Link 10/2021 - 01/2018
5	Messenger RNA (mRNA)IBA 08/2021 - 01/2008
5	TenascinIBA 01/2017 - 01/2013
4	VaccinesIBA 03/2024 - 01/2021
4	Monoclonal AntibodiesIBA 01/2022 - 05/2021
4	Protein Isoforms (Isoforms)IBA 10/2021 - 01/2012
4	CholesterolIBA 11/2018 - 12/2014
4	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 11/2016 - 03/2004
3	LipidsIBA 01/2024 - 01/2018
3	mRNA VaccinesIBA 11/2023 - 04/2021
3	Paclitaxel (Taxol)FDA LinkGeneric 01/2022 - 01/2003
3	DecorinIBA 01/2022 - 12/2006
3	Mevalonic Acid (Mevalonate)IBA 01/2021 - 12/2014
3	Indicators and Reagents (Reagents)IBA 10/2018 - 01/2003
3	EnzymesIBA 06/2018 - 01/2002
3	Biomarkers (Surrogate Marker)IBA 01/2018 - 01/2017
3	Small Interfering RNA (siRNA)IBA 01/2018 - 11/2012
3	Hormones (Hormone)IBA 01/2018 - 04/2002
3	CXC ChemokinesIBA 07/2015 - 06/2003
3	Phosphotransferases (Kinase)IBA 04/2014 - 09/2005
2	Immunoglobulin G (IgG)IBA 11/2023 - 07/2021
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2023 - 10/2021
2	Oxygen (Dioxygen)IBA 01/2022 - 05/2021
2	RNA (Ribonucleic Acid)IBA 01/2022 - 11/2012
2	casirivimab and imdevimab drug combinationIBA 01/2022 - 01/2022
2	AntibodiesIBA 04/2021 - 01/2021
2	Mitomycin (Mitomycin-C)FDA LinkGeneric 01/2021 - 10/2020
2	InflammasomesIBA 01/2021 - 10/2017
2	FurinIBA 11/2020 - 06/2020
2	Neutralizing AntibodiesIBA 11/2020 - 06/2020
2	Extracellular Matrix ProteinsIBA 01/2020 - 07/2006
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 12/2019 - 07/2015
2	Interleukin-8 (Interleukin 8)IBA 01/2018 - 01/2017
2	Microfilament Proteins (Actin Binding Proteins)IBA 01/2018 - 02/2009
2	Tyrosine (L-Tyrosine)FDA Link 01/2018 - 01/2010
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2018 - 06/2012
2	PolymersIBA 01/2017 - 09/2007
2	Glucose (Dextrose)FDA LinkGeneric 01/2017 - 12/2016
2	AndrogensIBA 01/2017 - 04/2002
2	Janus KinasesIBA 11/2016 - 06/2005
2	Protein Kinases (Protein Kinase)IBA 11/2016 - 05/2006
2	PlatinumIBA 07/2015 - 01/2003
2	Fibronectins (Fibronectin)IBA 09/2013 - 07/2006
2	4- ((3- bromophenyl)amino)- 6,7- dimethoxyquinazolineIBA 11/2012 - 01/2012
2	VimentinIBA 04/2012 - 02/2010
2	Gonadotropin-Releasing Hormone (GnRH)FDA Link 01/2012 - 04/2002
2	Peptide Hydrolases (Proteases)FDA Link 03/2011 - 10/2008
2	CXCR3 ReceptorsIBA 04/2010 - 09/2008
2	Profilins (Profilin)IBA 05/2009 - 02/2009
2	Chemokine ReceptorsIBA 01/2009 - 09/2005
2	Phospholipase C gammaIBA 07/2008 - 03/2004
2	1- (6- ((3- methoxyestra- 1,3,5(10)- trien- 17- yl)amino)hexyl)- 1H- pyrrole- 2,5- dioneIBA 07/2008 - 09/2003
2	Growth Factor ReceptorsIBA 05/2006 - 01/2002
2	Phospholipases (Phospholipase)IBA 09/2003 - 01/2003

Therapy/Procedure

24	Therapeutics 03/2024 - 01/2003
11	Drug Therapy (Chemotherapy) 01/2022 - 01/2003
2	Art Therapy 03/2024 - 01/2022
2	Immunotherapy 01/2022 - 10/2020
2	Filtering Surgery 01/2021 - 10/2020
2	Trabeculectomy (Trabeculoplasty) 01/2021 - 10/2020
2	Bioreactors (Bioreactor) 01/2013 - 01/2007